The City College Plymouth currently operates at two campuses, one at Plymouth near Lipson and another one at Piquet Barracks. Apart from this, the college also had another campus at the Goschen Centre in Keyham, which focused on science, technology, engineering, and maths (STEM). However, in order to build a new STEM building at the foundational Kings Road campus, the Keyham campus was shut down in the autumn of 2016.
Located in Plymouth on King's Road, the City College Plymouth Kings Road campus houses refurbished engineering Centre, smaller STEM Centre and a Regional Centre of Excellence for STEM which intends to train students in key priority sectors for the City, which imitates 'real-world environment across a range of industry sectors. The college also hosts a Marine Training Centre supported by Princess Yachts International plc, which provides specialist marine training for apprentices and students aged between 16 to 18, undertaking full-time courses related to marine engineering and other nautical related programs.
Located at Cumberland Road, Devonport, the Picquet Barracks offers its students with facilities including Engineering Workshops, I.T Suite, and Milo's Munchies Cafe. The campus also houses the Picquet Barracks Ocean Suite along with the Training and Reception Building.